Synthesis of Heterocyclic Compounds Via Chalcone Derivatives and Study Activity of Some these Compounds as Pesticides (Anti-Dubas)

In this research, we synthesized oxazine and thiazine derivatives (3-6). These of chacone compounds (1 2) that from 4- hydroxyacetophenone aldehyde such as, 4-bromobenzaldehyde chlorobenzaldehyde. chalcone (1-2) reacted with urea to produce as 4-[4-amino-6-(4-subsutitedphenyl)-2H-1,3-oxazin-2-yl] phenol (3 4) thiourea 4-[4-amino-6-(4-subsutitedphenyl)-2H-1,3-thiazin-2-yl] (5 6). were characterization by spectroscopy methods FTIR 1HNMR. Some 5) tested Pesticides (anti-dubas) through the spray method these killed Dubas noted compound 5 was more active 3 because have been S atom in his structure bonded group dubas effect on Cholinesterase enzyme insect.